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24. August 2006
TopoTarget and CuraGen announce Southwest Oncology Group opens new lymphoma trial with PXD101


18. August 2006
Epigenomics announces change in the Executive Board


10. August 2006
TopoTarget and CuraGen Initiate Clinical Program Evaluating Oral Administration of PXD101 - Phase I trial to establish the dose and frequency for oral PXD101 in patients with advanced solid tumors -


7. August 2006
Epigenomics AG Enters into Agreement with Johnson &Johnson Pharmaceutical Researach &Development, L.L.C


27. July 2006
US Patent Granted for 4SC’s Clinical Project


21. July 2006
Epigenomics AG Decides Capital Increase − Affymetrix Signs For New Shares


17. July 2006
KeyNeurotek AG Strengthens Finance and Clinical Development Management


14. July 2006
TopoTarget and CuraGen Announce Initiation of Phase I/II Trial of PXD101 for Hepatocellular Cancer


5. July 2006
Epigenomics AG Presents New Clinical Data on Colorectal Cancer Screening Markers


4. July 2006
DeveloGen receives Grant for DiaPep277® Program


29. June 2006
Ardana appoints new non-executive to the board


28. June 2006
4SC announces further research collaboration with Solvay




27. June 2006
Epigenomics AG and Affymetrix announce Strategic Diagnostics Platform Agreement


26. June 2006
Epigenomics AG and Wellcome Trust Sanger Institute Release Epigenetic Data on the first 3 Chromosomes


21. June 2006
DeveloGen AG: DiaPep277® mechanism of action demonstrated


15. June 2006
Probiodrug Closes a EUR 10.6 Million (US$ 13.4 million) Series C Financing Round


13. June 2006
DeveloGen AG und ihr Vorstandsvorsitzender Dr. Günther Karmann trennen sich in gegenseitigem Einvernehmen; Dr. Cord Dohrmann, Chief Scientific Officer, in den Vorstand berufen


8. June 2006
Epigenomics AG announces Research Collaboration with Stanford University


24. May 2006
elbion AG Increases Series A Financing to €35 Million


16. May 2006
Epigenomics AG Announces Continuation of Pharmaceutical Biomarker Research
Collaboration with AstraZeneca in the Field of Oncology



15. May 2006
4SC reports results of first quarter


12. May 2006
Epigenomics Receives Award for Best Oral Presentation at MipTec 2006


11. May 2006
4SC completes capital increase


3. May 2006
Epigenomics AG Reports First Quarter 2006 Results


3. May 2006
Ardana announces block lisiting


25. April 2006
Qiagen Eliminates Key Bottleneck in Epigenetic Research


24. April 2006
Designed for easy operation: Xenon - Klotz Digital's latest all-in-one mixer revealed at NAB 2006


12. April 2006
Ardana announces positive phase II results for testosterone cream


12. April 2006
4SC compound active against influenza viruses


5. April 2006
Clinical Study Proves Prognostic Power of Epigenomics' Biomarker in Prostate Cancer



3. April 2006
Epigenomics Presents Data Confirming Screening for Methylated DNA in Blood as Key to Early Colorectal Cancer Detection



30. March 2006
4SC AG reports financial results for financial year 2005


24. March 2006
Epigenomics AG Reports Financial Results for Fiscal Year 2005


22. March 2006
Epigenomics AG Reports Extension of Blood Screening Product Collaboration


17. March 2006
Ardana appoints Klaus Falk as VP Sales & Marketing


15. March 2006
Avontec GmbH starts new research laboratory at Heidelberg University
Groundbreaking research into transcription factor technology continues – target indications include severe asthma and inflammatory skin diseases


10. March 2006
Epigenomics Confirms Lead Marker for Prediction of Breast Cancer Relapse


28. February 2006
GPC Biotech to Present at Two Upcoming Conferences in the U.S.


27. February 2006
GPC Biotech Presents New Satraplatin Clinical Data from Pharmacokinetics Study at ASCO Prostate Cancer Symposium
New preclinical data on efficacy of satraplatin in prostate cancer cells and with Taxotere® also presented


24. February 2006
GPC Biotech Raises € 36.2 Million in Private Placement with SAP Co-Founder Dietmar Hopp


14. February 2006
BioWa and Aphton Announce Licensing of BioWa’s POTELLIGENT™ Technology
Aphton to Use BioWa’s POTELLIGENTTM Antibody Technology for Development of Preclinical IGN312 Anti-Lewis Y antibody


14. February 2006
BioWa and Aphton Announce Licensing of BioWa’s POTELLIGENT™ Technology
Aphton to Use BioWa’s POTELLIGENTTM Antibody Technology for Development of Preclinical IGN312 Anti-Lewis Y antibody


14. February 2006
European Regulatory Committee Recommends Orphan Drug Status for GPC Biotech’s Anticancer Monoclonal Antibody 1D09C3 for Multiple Myeloma


7. February 2006
Aphton to expand licensing and commercialization agreement into Europe for IGN311


31. January 2006
DeveloGen receives JDRF Grant for Beta-Cell Regeneration Program


31. January 2006
Ardana's novel testosterone cream remains on track for Q4 2007 launch following Pre-Ind Meeting with US FDA
Company completes Phase II dose-finding study enrolment


30. January 2006
Epigenomics AG Pursuing Development of Tamoxifen Response Test


27. January 2006
GPC Biotech AG: Orphan Drug Designation Granted by European Commission for Anticancer Monoclonal Antibody 1D09C3 for Chronic Lymphocytic Leukemia


17. January 2006
4SC enters next phase of drug discovery collaboration with Sanwa Kagaku Kenkyusho


11. January 2006
DeveloGen Announces Changes to Scientific Advisory Board


10. January 2006
elbion AG Completes € 25 Million Series A Financing


4. January 2006
Epigenomics Successfully Completes Biomarker Validation Study for Prostate Cancer Classification Test

Product Forms Foundation of Company's Tissue-Based Product Pipeline


4. January 2006
Epigenomics AG adds Regulatory Affairs and Marketing Expertise to Senior Management



19. December 2005
Epigenomics DNA Methylation Test Successfully Detects Colorectal Cancer in Blood
Clinical Studies Demonstrate Proof-of-Concept for Early Detection of Disease


15. December 2005
4SC AG: Share trading at the Frankfurt Stock Exchange


13. December 2005
Milestone and Licensing decision on tamoxifen response test postponed to end of January 2006


13. December 2005
Successful completion of financing round totalling € 7.75 million
KeyNeurotek AG takes over Sirenade Pharmaceuticals AG


7. December 2005
Aphton Announces Receipt of NASDAQ Notice of Non-Compliance;
Aphton to Appeal



30. November 2005
Pre-listing capital increase successfully completed / Application for stock exchange listing filed



25. November 2005
Aphton Corporation Announces Closing of Long-Term Debt Restructuring


17. November 2005
Aphton Announces Closing of Commercialization and Manufacturing Agreements for IGN311 with Celltrion


15. November 2005
Epigenomics AG announces end of VC pooling




15. November 2005
Aphton announces adoption of mandatory retirment policy for the board of directors


9. November 2005
Aphton announces mutual agreement to dissolve co-promotion and licensing agreemnet related to anticancer product INSEGIA™ with Sanofi Pasteur


9. November 2005
Ardana signs Agreement with PHARMACURO to market STRIANT™ SR in the nordic region


2. November 2005
Epigenomics AG reports third quarter 2005 financial results


31. October 2005
Epigenomics reports Tamoxifen treatment response test study results inconclusive


31. October 2005
Ardana announces positive Phase I results and starts Phase II trials for NOVEL testosterone cream


5. October 2005
Ardana announces german lounch of STRIANT™ SR through CYTOCHEMIA AG


5. October 2005
DeveloGen Announces End-of-Phase II Meeting with FDA, EMEA Scientific Advice Meeting and First-Patient-In for Phase III Clinical Trial of DiaPep277®


30. September 2005
Epigenomics and Roche Diagnostics extend R&D collaboration agreement
Epigenomics AG (Frankfurt, Prime Standard: ECX), a molecular diagnostics company developing tests based on DNA methylation, today announced an extension to its existing agreement with Roche Diagnostics, a world leader in molecular diagnostics. The R&D part of the collaboration, which covers the development of five cancer diagnostic tests, has been extended for a minimum of 6 months, with the option to prolong and potentially expand for another 18 months. Financial terms were not disclosed.


27. September 2005
TOPOTARGET AND CURAGEN INITIATE PHASE Ib CLINICAL TRIAL WITH PXD101 FOR ADVANCED COLORECTAL CANCER

- Proof-of-concept trial evaluating PXD101 combination therapy with 5-fluorouracil for advanced solid tumours and colorectal cancer -


21. September 2005
Ardana accelerates anticipated launch of Teverelix Long Acting (LA) in benign prostatic hyperplasia following pre-ind meeting with the US FDA
Ardana plc (LSE:ARA), the emerging pharmaceutical company focused on improving human reproductive health, today reports that the launch of its lead compound, the GnRH antagonist Teverelix Long Acting (LA) in benign prostatic hyperplasia (BPH), could be advanced by up to two years, following a pre-Investigational New Drug (IND) application meeting with the FDA at which consensus on the company’s development plan for the therapy was reached. It was previously expected that Teverelix in BPH could reach the market in 2012.


20. September 2005
Elbion AG appoints Dr. Thomas Taapken as Chief Financial Officer and Member of the Executive Board
elbion AG, a Radebeul (Germany) based and privately held, biopharmaceutical company dedicated to the development of novel small molecule drugs in the areas of inflammation and CNS disorders, announced today that Dr. Thomas Taapken has been appointed Chief Financial Officer by the supervisory board of the company.


14. September 2005
DeveloGen Presents Positive Phase II Data at EASD Conference
DeveloGen, a biopharmaceutical company focusing on novel treatments for metabolic disorders, today presented positive results of two phase II clinical trials of DiaPep277® for the treatment of type 1 diabetes at the 41st Annual Meeting of the European Association for the Study of Diabetes (EASD) in Athens


12. September 2005
Epigenomics AG announces resignation of Aron Braun


7. September 2005
Clinical development of Ardana's Teverelix Long Acting (LA) in prostate cancer continues on track following pre-IND application meeting with the United States Food & Drug Administration (FDA)


30. August 2005
With the New Development candidate NSD-551 TopoTarget and Neurosearch expand their collaboration within cancer treatment


17. August 2005
4SC appoints new Chief Financial Officer and announces changes to Supervisory Board


16. August 2005
Debiopharm and DeveloGen Announce Partnering of Myasthenia Gravis Program


15. August 2005
Retiring Epigenomics executive Gary Schweikhardt released from lock-up at year-end


9. August 2005
TopoTarget receives $4.8 million milestone payment from Curagen Corp as ongoing Phase II trial of PXD101 is extended to the United States
- Study evaluating PXD101 in multiple myeloma scheduled for completion mid 2006 -


4. August 2005
TopoTarget A/S - Capital increase as a result of emmployee warrant exercise


3. August 2005
Epigenomics AG report second quarter and first half 2005 financial results


2. August 2005
Epigenomics AG announces Gary Schweikhardt to retire


26. July 2005
Acquisition of GlycArt Biotechnology completed


19. July 2005
Roche acquires Swiss based GlycArt Biotechnology to strengthen expertise in therapeutic antibody research


12. July 2005
4SC receives financing trough new technology funds from KfW and Bayern Kapital


7. July 2005
US FDA grants TopoTarget Orphan Drug Designation (ODD) for PEAC® in patients with FAP, a genetic predisposition to colon cancer


28. June 2005
TopoTarget A/S – Full exercise of over-allotment option


28. June 2005
SAVENETM (dexrazoxane) demonstrates 97% success rate in Phase II/III trial to treat accidental extravasation of anthracycline anti-cancer agents
- TopoTarget closes patient enrollment as requisite number of subjects is recruited -


17. June 2005
Ardana appoints New Non-Executive to The Board


16. June 2005
Ardana signs agreement with Cytochemia to market Striant™ SR in Germany


6. June 2005
Aphton announces appointment of Manfred Ruediger, Ph.D. to the position of Chief Operating Officer


1. June 2005
DeveloGen appoints New Scientific Advisory Board and announces changes in Senior Management Team


26. May 2005
Ardana announces successful results in a Phase II Study of Teverelix LA in Benign Prostatic Hyperplasia


24. May 2005
elbion AG increases Series A financing to € 35 million


23. May 2005
TopoTarget receives broad US and EU patents for key HDAC inhibitors
Awards strengthen Company’s leading HDAC inhibitor drug development programme


17. May 2005
Epigenomics AG validates DNA methylation test as predictor of disease recurrence in breast cancer patients
Data presented at ASCO and published in cancer research provides valuable information to guide treatment options


17. May 2005
TopoTarget and CuraGen present PXD101 Phase I results at ASCO
Preliminary data suggests PXD101 is well tolerated following oral or intravenous administration


12. May 2005
Ardana announces successful results in second Phase II of Teverelix LA in prostate cancer


12. May 2005
TopoTarget and CuraGen announce co-operative R&D agreement with US National Cancer Institute for PXD101


10. May 2005
4SC receives BMBF grant for development of new drug candidates for treatment of multiple sclerosis


4. May 2005
Epigenomics AG reports first quarter 2005 results


2. May 2005
Epigenomics AG and QIAGEN enter into strategic collaboration in DNA Methylation
Leading preanalytical solutions for methylation analysis to focus on in-vitro molecular diagnostics and pharmacogenomics markets


20. April 2005
New preclinical data on HDAC inhibitor PXD101 demonstrates down regulation of common mechanism of cancer therapy resistance
- Results presented at the AACR 96th Annual Meeting -


20. April 2005
Epigenomics AG presents positive data at AACR
Epigenomics AG presents positive prognostic biomarker data from studies in prostate and breast cancer at AACR


19. April 2005
Ardana announces positive results in Phase I study of oral Growth Hormone Secretagogue


5. April 2005
4SC and Schwarz Pharma agree on long-term research cooperation


24. March 2005
Apthon announces closing of Igeneon acquisition


24. March 2005
4SC successfully concludes Phase I study for product candidate for the treatment of autoimmune diseases


23. March 2005
GLYCART biotechnology appoints Andreas Emmenegger as Chief Financial Officer


23. March 2005
Epigenomics AG reports financial results for fiscal year 2004


16. March 2005
TopoTarget A/S raises Euro 15 million and attracts new investor
- Series C funding will support clinical development until first product launches -


14. March 2005
Epigenomics AG to present data from breast cancer outcome prediction study


4. March 2005
Ardana announces successful completion of IPO


1. March 2005
TopoTarget A/S acquires G2M Cancer Drugs AG
- Move creates strong oncology company with dominance in the field of HDAC inhibitors -


17. February 2005
Ardana announces successful results in Phase II trial of Teverelix in prostate cancer


15. February 2005
4SC and Sanwa Kagaku Kenkyusho enter into multi-year drug discovery collaboration


2. February 2005
Ardana signs three-year extension to its exclusive agreement with MRC Human Reproductive Sciences Unit
- Deal gives Ardana first option on strategic research projects -


20. January 2005
Epigenomics AG announces end of IPO Lock Up period


21. December 2004
Epigenomics achives key milestone in development of prostate cancer classification test
Company discovers biomarkers for prostate cancer aggressiveness


15. December 2004
Aphton Corporation to acquire igeneon extending its leadership position in cancer immunotherapy
Acquisition represents pivotal step to establishing a broad oncology franchise


2. December 2004
Epigenomics AG and Roche Diagnostics expand R&D structure of collaboration


18. November 2004
Morphochem and Probiodrug collaborate in research and development of novel innovative dipeptidyl peptidase IV (DP IV) inhibitors for the treatment of Anxiety and Depression


9. November 2004
DeveloGen receives R&D Funds for diabetic Complications Project
German Federal Ministry of Education and Research supports Research Project


8. November 2004
igeneon announces survival data of Phase II trial with IGN101 cancer vaccine
Statistically significant survival prolongation in group of patients with metastatic rectal cancer


3. November 2004
Epigenomics AG reports third quarter 2004 results


2. November 2004
4SC achieves milestone in research collaboration with Sonofi-Aventis


28. October 2004
Ardana receives Special Biotechnology Award for second year running in Deloitte & Touche Fast 50 celebrations


28. October 2004
Ardana announces completion of European Mutual Recognition Process for StriantTM testosterone replacement therapy in men with primary of secondary hypogonadism


20. October 2004
igeneon names Guenter Schirmer, M.D., Ph.D., Medical Director


12. October 2004
Sirenade Pharmaceuticals announces breakthrough in the development of Tau-Directed therapeutics to treat Alzheimer’s Disease


7. October 2004
Epigenomics forms pharmacodiagnostic research collaboration with Biogen Idec in oncology


5. October 2004
aws to back igeneon cancer research program
EUR 5 million loan guarantee for development of innovative cancer drugs


29. September 2004
Sirenade Pharmaceuticals appoints Lynn Butler as CEO and restructures management team


22. September 2004
GLYCART biotechnology to present at UBS 2004 Global Life Sciences Conference


21. September 2004
Roche and GLYCART to discover new therapeutic antibodies


21. September 2004
4SC AG and MUTABILIS S.A. collaborate in the field of infectious diseases


24. August 2004
Initial public offering of Epigenomics AG: end of stabilization period


16. August 2004
Closing of Probiodrug-Prosidion transaction and changes in management & board


12. August 2004
Epigenomics AG meets key milestone in breast cancer test development


2. August 2004
Ardana appoints Vice-President of Pre-Clinincal Sciences


16. July 2004
Epigenomics listing to occur Monday July 19, 2004
Epigenomics prices IPO on Frankfurt Stock Exchange at € 9.00 per share


7. July 2004
Solvay Pharmaceuticals selects Sirenade as protein structure service provider


6. July 2004
Probiodrug awarded a €1.9mio BioChancePlus grant to fund a drug-discovery program for the treatment of neurodegenerative disorders


29. June 2004
Ardana appoints two Non-Executive Directors to the Board


21. June 2004
Senetek licenses Invicorp® erectile dysfunction treatment to Ardana for Europe
Ardana to assume full regulatory responsibility and Senetek to receive royalities and milestone payments


18. June 2004
Osi Pharmaceuticals’ Subsidary Prosidion Acquires Dipeptidyl Peptidase IV Platform From Probiodrug - Includes Phase II Development Candidate P93/01 -


17. June 2004
Manfred Ruediger appointed new CEO of igeneon
Founder Hans Loibner to retire after 5 years at the helm


14. June 2004
Sirenade Pharmaceuticals AG initiates Phase I study with SRN-001 (DHEC)


8. June 2004
4SC AG announces grant of US patent for computer-aided screening method


7. June 2004
Epigenomics presents positive results from studies using DNA methylation markers for predicting disease recurrence in breast cancer patients


3. June 2004
Ardana strengthens senior management team
Mr Simon Best appointed as Chairman, Dr Maureen Lindsay appointed as Chief Executive Officer and Mr Graham Lee appointed as Chief Financial Officer


3. June 2004
UK launch for Ardana's Striant SR testosterone replacement therapy for men with primary or secondary hypogonadism


28. May 2004
Ardana completes extension to Series B fundraising


17. May 2004
DeveloGen completes 19 million Euro financing round


12. May 2004
Update on Probiodrug's Patents


12. May 2004
AVONTEC appoints Chief Financial Officer and completes management team


10. May 2004
Sirenade Pharmaceuticals AG and Polichem S.A. sign an exclusive license agreement in CNS


4. May 2004
4SC AG and Serono sign worldwide agreement to develop and commercialize
orally active compounds for the treatment of autoimmune disorders

- Lead Compound SC12267 Completing Phase I Clinical Trials -


28. April 2004
SIRENADE Pharmaceuticals AG announces the appointment of Dr. Wolfgang Schuette as Chief Medical Officer


27. April 2004
Epigenomics and academic partners receive BMBF grant to develop novel techniques for early cancer detection based on DNA-methylation


25. April 2004
igeneon raises EUR 26.7 million in a Series C financing round co-led by Burrill & Company and 3i


30. March 2004
Joint forces against vitiligo - development co-operation agreement signed with Spirig Pharma for vitiligo product


23. February 2004
4SC AG spins off quattro research GmbH - a company which develops and markets software solutions for the life science industry


11. February 2004
AVONTEC appoints VP Product Development


20. January 2004
Epigenomics develops technique for sensitive early detection of cancer


13. January 2004
Epigenomics to enter collaboration with AstraZeneca
Project to use paraffin samples for the identification of biomarkers


13. January 2004
NADAG and SiREEN announce merger to form SIRENADE Pharmaceuticals AG and launch €20 million financing round


7. January 2004
igeneon expands management board in 2004

Dr. Manfred Rüdiger new Chief Operating Officer


16. December 2003
Probiodrug´s meeting of the Scientific Advisory Board highlighted programs in metabolic and neuronal disorders


16. December 2003
Epigenomics and Wyeth to enter collaboration
Project to identify drug response markers


15. December 2003
Probiodrug AG Reported on the Results of its Clinical Phase IIa Trial with the DPIV Inhibitor P93/01 in Type 2 Diabetes and its Patent Licensing Programs


10. December 2003
4SC AG starts phase I study of product candidate for treatment of rheumatoid arthritis


26. November 2003
GLYCART Biotechnology closes $13.6 million private financing round


20. November 2003
AVONTEC successfully completes phase I clinical trials for its first product candidate


17. November 2003
4SC appoints Patrick Schwarz-Schütte, Dr Brian Morgan and Dr Holger Reithinger to its supervisory board


14. November 2003
First Clinical Results in the Treatment of Psoriasis


13. November 2003
Peptor and DeveloGen announce intention to merge


11. November 2003
igeneon initiates further pivotal Phase III clinical trials with IGN101 cancer vaccine
  • Controlled Phase III study in metastatic colorectal cancer

  • First controlled Phase III study with a cancer vaccine in adjuvant breast cancer worldwide


30. October 2003
igeneon presents at "International Society for Biological Therapy of Cancer" (iSBTc) 18th Annual Meeting
  • Lecture on disseminated tumor cells as surrogate marker in cancer therapy

  • Presentation of latest clinical developments in its cancer immunotherapy product portfolio


20. October 2003
AVONTEC’s First Compound to Enter Clinical Development


20. October 2003
SWITCH Biotech appoints Stefan Schulze Chief Executive Officer


13. October 2003
SWITCH Biotech selects 4SC as partner for the discovery and development of active compounds for the treatment of Psoriasis


13. October 2003
SiREEN AG received a research grant for its innovative cancer research program from the Bavarian Ministry of Economics.


7. October 2003
Epigenomics and the Wellcome Trust Sanger Institute launch Human Epigenome Project to follow EU-pilot study


10. September 2003
DeveloGen and Evotec OAI announce a strategic drug discovery and development alliance for metabolic diseases


9. September 2003
AVONTEC Receives Key Patent in the US


5. September 2003
Probiodrug's DPIV inhibitor P93/01 for the treatment of type 2 diabetes in patients


3. September 2003
SiREEN AG and its academic collaboration groups are awarded with a research grant from the Bavarian Research Foundation


20. August 2003
Certification according to DIN EN ISO/ICE 17025:2000


22. July 2003
Roche expands the strength of its product franchise in Rheumatoid Arthritis and Transplantation
Roche acquires Cardion’s promising IL-15 antagonist


15. July 2003
4SC and Esteve agree on broadening their research partnership


13. July 2003
igeneon presents at Late Breaking Poster Session at AACR (American Association for Cancer Research) meeting
  • Monoclonal antibody IGN311 data show additional mechanism of action similar to Herceptin® and Erbitux®

  • Co-expression of igeneon's targets correlates with poor prognosis in breast cancer


9. July 2003
EPIGENOMICS spins off start-up Epiontis
DNA-methylation is applied in cell therapy and tissue engineering


25. June 2003
AVONTEC receives German Founders Award


3. June 2003
Avontec appoints new CEO


2. June 2003
igeneon presents cancer vaccine IGN101 Phase II data at the annual American Society of Clinical Oncology (ASCO) meeting
  • Results show high immunogenicity despite concomitant chemotherapy

  • Permits further testing in wide range of clinical settings


21. May 2003
4SC AG coses nine million Euro third round financing


9. May 2003
igeneon presents new scientific results at renowned international cancer congresses
  • Presentations at ASCO and AACR

  • Co-sponsor of iSBTc/Focis satellite symposium "Cellular Immunology and Immunotherapy of Cancer"


28. April 2003
4SC and ProQinase collaborate on the discovery of new protein kinase inhibitors for cancer treatment


3. April 2003
Epigenomics raises € 21 (US$ 22.5) million in a third round of financing


27. March 2003
New Chief Development Officer
SWITCH Biotech AG appoints new Chief Development Officer for the future clinical development phases of trial substances


27. March 2003
AVONTEC GmbH recruits several internationally renowned scientists to form its Scientific Advisory Board


24. March 2003
SiREEN AG selects Evotec OAI as a partner to identify novel small molecule inhibitors against one of its targets


18. March 2003
Roche and Epigenomics sign broad cancer diagnostics alliance
Companies to collaborate on diagnostic products for early cancer detection, classification, and treatment reponse


18. March 2003
Epigenomics licenses marker in blood from Johns Hopkins University that may indicate predesposition to colon cancer
Potential To Develop First Test For Colon Cancer Predisposition From A Blood Sample


10. March 2003
First native DP IV-structure solved


27. February 2003
Further US-patent issued


25. February 2003
4SC and Boehringer Ingelheim sign research agreement for the identification of novel drug candidates against three targets


18. February 2003
igeneon and Immunicon form development alliance
  • Cooperation between bio pharmaceutical and diagnostic companies on clinical studies to bring product development synergies and cost savings

  • Potential for acceleration of time-to-market for cancer immunotherapies


17. February 2003
CARDION announces Licence of Genomics Enabler™ Technology to Pfizer Inc.


12. February 2003
Exclusive licence to Medication for the treatment of skin diseases


31. January 2003
4SC appoints vice president medicine to support the advancement of key drug candidates into clinical trials


30. January 2003
Danish LEO Pharma obtains license from SWITCH Biotech


27. January 2003
Epigenomics accesses additional DNA methylation technologies for early detection of tumors and expands its scientific advisory board


17. January 2003
DeveloGen and scientists from IPK Gatersleben publish data on key trigger for regenerating Insulin Producing Cells
-- Study provides additional support in fight to treat diabetes --


16. December 2002
4SC and academic research consortium receives EU grant to develop new drugs to treat S.Aureusinfections


12. December 2002
igeneon initiates Phase I clinical studies of two key cancer products and reaches major milestone
  • FDA accepts IND for IGN301 allowing The Cleveland Clinic and igeneon to start joint Phase Ib study in U.S.

  • IGN311 humanized antibody starts Phase I study at Augsburg Central Clinic

  • igeneon now has three key products in clinical development


18. November 2002
probiodrug and Synt:em announce collaboration to develop compounds for certain drug targets for CNS


11. November 2002
4SC archieves first milestone in research collaboration with recordati to identifY novel drug candidates


5. November 2002
Epigenomics and Mayo Clinic collaborate on test for early detection of colorectal cancer


31. October 2002
igeneon strengthens project management organization


11. October 2002
SWITCH Biotech restructures its activities
Focussing on the future


3. October 2002
Protarga to begin Pivotal Phase III study of new cancer drug
In Patients with Metastatic Melanoma

Clinical program to be presented at UBS Warburg conference in New York


2. October 2002
igeneon acquires cancer vaccine license - Further development of former Novartis product in Europe and the USA


25. September 2002
probiodrug grants license to Ferring and Ortho McNeil Pharmaceuticals


23. September 2002
CARDION closed € 11.5 million financing round


3. September 2002
DeveloGen appoints Dr. Klaus Brandau as Chairman of the Supervisory Board


31. July 2002
igeneon strengthens its management team


31. July 2002
Leading immunologist joins igeneon's Scientific Advisory Board - Ivan Roitt advising igeneon


29. July 2002
Protarga and ICOS begin research collaboration on new anti-cancer compounds
Application of Targaceutical® Technology to novel anti-cancer agents


29. July 2002
Protarga and ICOS begin research collaboration on new anti-cancer compounds
Application of Targaceutical® Technology to novel anti-cancer agents


11. July 2002
igeneon licenses humanized antibody in cancer from Protein Design Labs


10. July 2002
LEO Pharma and SWITCH Biotech
Stocktaking after an exceptional year of co-operation with
LEO Pharmaceutical Products Ltd. A/S


27. June 2002
Biopsytec closes second round financing over € 5 million.


20. June 2002
SWITCH Biotech is awarded the preliminary Work and Family Audit
At the cutting edge of the Biotechnology sector


12. June 2002
Epigenomics' CEO Alex Olek receives first annual German StartUp award


10. June 2002
4SC decides to use IBM Linux Cluster technology, based on the eServer xSeries, for drug discovery


23. May 2002
Epigenomics CEO Alex Olek named one of the the world’s top young innovators by TECHNOLOGY REVIEW


16. May 2002
International prizes for research projects supported by SWITCH Biotech
Double recognition for wound healing


7. May 2002
Protarga announces additions in oncology and clinical development
Frank Bambarola appointed Vice President, Oncology and Timothy McKinlay appointed Senior Director, Clinical Operations


30. April 2002
SWITCH Biotech concludes third round of financing
First investor from USA


26. April 2002
SWITCH Biotech strengthens its business development


25. April 2002
Epigenomics and Biopsytec cross-license revolutionary genetic based technologies


17. April 2002
DeveloGen names Dr. Günther Karmann as CEO

Dr. Thomas Metz also appointed to newly created position of VP, Lead Discovery


3. April 2002
SWITCH Biotech offers a family-friendly working environment
Competitive with 32 children?


27. March 2002
DeveloGen announces support of diabetes research by the European Comission


14. March 2002
SWITCH Biotech lays the foundations for co-operation with Japan
Martinsried greets Japan with a "Konnichi wa"


6. March 2002
DeveloGen announces senior management appointments in business development and research


28. February 2002
SWITCH Biotech expands its vitiligo network - cooperation with the Charité in Berlin
Goal: A Drug to Treat Vitiligo


25. February 2002
The Cleveland Clinic and igeneon to collaborate on new Cancer vaccine Research


29. January 2002
Cancer immunotherapy from igeneon: one step closer to marketability - the cancer vaccine IGN101 enters an extensive clinical trial in lung cancer patients


24. January 2002
SWITCH Biotech expands third round of financing
Equity increased by Euro 3.6 million


17. January 2002
The most recent findings concerning wound healing
SWITCH Biotech publishes articles in scientific journals


16. January 2002
Cancer immunotherapy from igeneon: one step ahead marketability - The cancer vaccine IGN101 enters the second clinical phase


14. January 2002
4SC and WILEX Sign cancer research collaboration to optimize second Generation UPA inhibitors